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Supply Chain Engineering

Senior Scientist, MSAT LM DS

  • Başlık Senior Scientist, MSAT LM DS
  • İşlev Supply Chain Engineering
  • Alt fonksiyon Process Engineering
  • Kategori Senior Engineer, Process Engineering (ST6)
  • Konum Leiden, South Holland, Netherlands
  • Postalanan
  • İstek Kimliği 2406223704W
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Johnson & Johnson is currently seeking a Senior Scientist, MSAT LM DS to join our Manufacturing Science and Technology (MSAT) Lab, located in Leiden, the Netherlands.

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com/.


Are you a highly motivated and results-oriented scientist with a deep understanding of downstream processes in Large Molecule manufacturing? Do you thrive in a dynamic and collaborative environment where you can contribute to the development of innovative therapies that improve patients' lives? If so, we invite you to join our team!

The MSAT Lab operates within the Large Molecule Drug Substance (LM DS) platform, which is a segment of the global MSAT organization.

As we work to enhance MSAT capabilities to fully own our current and future commercial products, we are establishing a dedicated MSAT LM DS Lab specializing in Large Molecules (mAbs, complex glycoproteins, bi- & tri-specifics). This lab will house small-scale equipment including 2-10 L bioreactors (fed-batch and continuous perfusion), downstream processing and process analytical lab equipment.

The MSAT Lab will support Life Cycle Management of commercial products and Secondary Technology Transfers. Our lab will conduct satellite runs in Leiden and for EU & Row address complex investigations, process improvements, and serve as a non-routine sample hub.

You will be a key contributor to our team, playing a vital role in complex investigations and enhancing the robustness and reliability of downstream processes for large molecules in our global commercial portfolio. You will work independently, while receiving guidance and support from the Principal Scientist, to execute experiments, analyze data, and contribute to the advancement of key projects.

If you are passionate about combining science with business applications and improving patient outcomes, we invite you to apply!

Key Responsibilities:

  • Downstream Process Investigations & Optimization:
  • Design, execute, and analyze experiments related to downstream processes, to address complex investigations, optimize step yields and increase robustness and reliability of our LM products.
  • Contribute to the development and implementation of robust and scalable downstream processes (reduced scale models).
  • Troubleshoot process challenges and identify potential improvements.
  • Data Analysis & Reporting:
  • Analyze experimental data independently and prepare clear and concise reports.
  • Effectively communicate results to colleagues and stakeholders.
  • Technical Expertise & Innovation:
  • Stay abreast of the latest advances and technologies in downstream process development.
  • Contribute to the development and implementation of technical solutions to address manufacturing challenges.
  • Collaboration & Communication:
  • Work collaboratively with other members of the MSAT team (both local and global), sharing knowledge and expertise.
  • Effectively communicate with colleagues and stakeholders, providing clear and concise updates on project progress.


Nitelik

  • Educational Background:

  • Advanced degree (MSc/MBA/PhD) in a relevant field, such as Biochemistry, Biotechnology, Chemical Engineering, or a related field.

  • Experience:

  • 4+ years with advanced degree MSc/MBA/Ph.D. or equivalent

  • OR 7+ years of relevant experience and Bachelor’s degree or equivalent

  • Hands-on experience with lab operations pertaining to chromatography, filtration, and process optimization.

  • Technical Skills:

  • In-depth understanding of downstream processes for large molecule drug substances, including chromatography, resins and filtration modes.

  • Proficiency in data analysis and interpretation.

  • Familiarity with regulatory guidelines and good manufacturing practices (GMP).

  • Problem-Solving & Analytical Skills:

  • Demonstrated ability to solve complex scientific and technical challenges independently and within a team setting.

  • Strong analytical skills, with the ability to critically evaluate data and draw sound conclusions.


For more than 130 years, diversity, equity & inclusion (DEI) has been a part of our cultural fabric at Johnson & Johnson and woven into how we do business every day. Rooted in Our Credo, the values of DEI fuel our pursuit to create a healthier, more equitable world. Our diverse workforce and culture of belonging accelerate innovation to solve the world’s most pressing healthcare challenges.

We know that the success of our business – and our ability to deliver meaningful solutions – depends on how well we understand and meet the diverse needs of the communities we serve. Which is why we foster a culture of inclusion and belonging where all perspectives, abilities and experiences are valued and our people can reach their potential.

At Johnson & Johnson, we all belong.


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