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Career Programs

CoOp

  • Título CoOp
  • Função Career Programs
  • Sub função Non-LDP Intern/Co-Op
  • Local Spring House, Pennsylvania, United States
  • Postado
  • ID obrigatória 2406165408W
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Descrição

Johnson & Johnson Innovative Medicine is recruiting for a Co-op, located in Spring House, PA Transcription/translation of GOI is influenced by many intrinsic proteins and regulatory elements in cell lines. It might be possible to modulate these controlling elements without enforcing metabolic engineering. To overcome transcriptional bottlenecks in antibody expression, we plan to implement an advanced gene regulation system in mammalian cell lines. This system, either constitutive or inducible, intends to precisely control the transcription of recombinant antibody expression cassettes, leveraging cutting-edge technology. This new technology will potentially allow for improving titers and critical quality attributes of antibodies in manufacturing CHO cell without targeted metabolic engineering and host cell line optimization.

Qualificações

Key Responsibilities:

The prospective candidate will perform molecular biology and mammalian cell culture activities including, but not limited to:

  • Implement molecular biology tasks including PCR, cloning, sequencing as part of daily responsibilities
  • Conduct mammalian cell culture activities, encompassing cell passaging, transfections, and single cell printing
  • Perform automated Western blotting, antibody titering, and gene and transcripts copy number analysis
  • Troubleshooting experimental procedures, and collaborating seamlessly with colleagues to champion a dynamic research environment
  • Engage in other relevant duties within the scope of molecular biology and cell culture responsibilities

Qualifications

Education:

  • Currently pursuing a Master's or PhD degree with major in Biology, Microbiology or Molecular Biology, or Chemical or Biological Engineering.

Experience and Skills:

Required:

  • Applicants must be available to work full-time for at least 6 consecutive months.
  • The candidate should demonstrate a strong interest in performing hands-on laboratory work.
  • Prior experience in molecular biology techniques is required.
  • Experience with handling cell culture under sterile conditions is required.
  • Proficient with Word, Excel, and PowerPoint.
  • Ability to work independently or in a team environment.
  • Good interpersonal skills to effectively present information both orally and in writing to diverse groups.

Preferred:

  • Proficient in comprehensive scientific literature searches
  • Courses taken in Biochemistry, Microbiology and Genetics will be beneficial

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

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