Johnson & Johnson Careers

Senior Scientist, Immunology Medicinal Chemistry

Spring House, Pennsylvania

Job Description

Requisition ID: 9456180418

Janssen Research & Development, L.L.C, a member of the Johnson & Johnson Family of Companies, is recruiting for a Senior Scientist, Immunology Medicinal Chemistry located in Spring House, PA.

Janssen Research & Development, LLC discovers and develops innovative medical solutions to address important unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, and cardiovascular and metabolic diseases. Please visit for more information.

We are seeking an experienced Medicinal Chemist with excellent organic synthesis expertise to advance small molecule drug discovery programs toward the clinic. The successful candidate will partner with the internal medicinal chemistry team to generate innovative solutions to synthetic and medicinal chemistry challenges within the context of small molecule drug discovery.

A practical knowledge of modern drug design, the application of chemoinformatics tools and experience advancing small molecule inhibitors of PPI targets towards the clinic would be advantageous. This individual must also excel in communication and have strong interpersonal skills necessary to influence in a collaborative multidisciplinary environment, and ideally have some leadership experience.


• Maintain a high level of productivity in the laboratory setting.
• Develop and execute clear synthetic strategies towards complex molecules using state-of-the-art synthetic methodologies.
• Independently design and synthesize drug-like molecules utilizing medicinal chemistry knowledge and an understanding of ADME, pharmacokinetics and optimal physicochemical properties.
• Collaboratively support the advancement of compounds through in vitro and in vivo studies to identify development candidates.
• Collaborate with structure based design groups to impact rational design of molecules.
• Generate novel, testable hypotheses to enable clear decision making.
• Manage external synthesis support.
• Contribute to defining scientific strategies and goals within a project team setting.
• Present data and reports on project status at individual, group, departmental and organizational meetings.
• Draft, execute and serve as lead author on research published in peer reviewed journals and present work at scientific conferences.
• Collaboratively engage with the external scientific community.
• Present data and reports on project status at individual, group, departmental and organizational meetings.

• A Ph.D. in synthetic organic chemistry with 3+ years pharmaceutical medicinal chemistry industrial experience (optionally 1-2 years post-doctoral experience) OR equivalent experience for non-Ph.D.’s performing progressively advanced duties beyond the Scientist level is required.
• Demonstrate a strong track record of achievement in synthesis of complex molecules with knowledge of modern synthetic, analytical techniques is required.
• Proven track record of scientific contributions including peer reviewed publications, patents and presentations is required.
• Demonstrate independent thinking and the ability to effectively collaborate in a highly matrixed environment.
• Excellent oral and written communication skills, including preparation of presentations.
• Up to 5% travel is required.

Johnson & Johnson Family of Companies are equal opportunity employers, and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, genetic information, national origin, protected veteran status, disability status, or any other characteristic protected by law.

Primary Location
United States-Pennsylvania-Spring House
Janssen Research & Development, LLC. (6084)
Job Function
Requisition ID