Senior Scientist, Immunological Toxicology (La Jolla, CA) 1 of 2 - Janssen Research & Development, LLC

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Job Description

Senior Scientist, Immunological Toxicology


Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies is recruiting for a Principal Scientist, located in Springhouse, PA or La Jolla, CA. 


At the Janssen Pharmaceutical Companies of Johnson & Johnson, we are working to create a world without disease. Transforming lives by finding new and better ways to prevent, intercept, treat and cure disease inspires us. We bring together the best minds and pursue the most promising science.  


We are Janssen. We collaborate with the world for the health of everyone in it. Learn more at and follow us @JanssenGlobal.  Janssen Research & Development, LLC is part of the Janssen Pharmaceutical Companies.  


Janssen Research & Development, LLC discovers and develops innovative medical solutions to address important unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, and cardiovascular and metabolic diseases. Please visit for more information.   

We are Janssen. Our mission drives us. Our patients inspire us. We collaborate with the world for the health of everyone in it. Thriving on a diverse company culture, celebrating the uniqueness of our employees and committed to inclusion. Proud to be an equal opportunity employer.   

The Senior Scientist in Immunological Toxicology (IT) will work as a member of IT to evaluate potential immune system-related risks associated with large and small molecule therapeutics in our pipeline.  The Senior Scientist will work under limited supervision to provide strategic and scientific input to multidisciplinary Project Teams – to progress therapeutics from discovery to first-in-human and beyond.  

As a Senior Scientist additional responsibility will include:   

  • Actively performs bench-based science for evaluating immune system-related effects. 

  • Interacts with CROs at multiple levels, including: transferring methods developed at Janssen, monitoring CRO validations, and the monitoring of immune endpoints during both GLP and non-GLP studies.

  • Designs, conducts and leads studies to evaluate the effects of immunomodulatory compounds using various in vivo and in vitro model systems including, but not limited to, cytokine assessment, immune response, flow cytometry and functional cell-based assays following Data Integrity standards, and writes reports for regulatory submission.

  • Investigates and develops novel experimental methods/technologies, contributes to improvement of existing methods and develops new in vitro/in vivo models to enhance our understanding of potential immunotoxicology risk and translatability to humans in the clinic.

  • Participates in communication of information and data presentation in oral and written format to stakeholders.

  • Authors and reviews formal study reports in compliance with discovery data integrity principles.




  • Experience in pharmaceutical/biotechnology research management or related experience in drug development is preferred

  • Knowledge of GLPs is preferred

  • Previous experience managing external partnerships (CRO’s) is preferred

  • Strong leadership skills with highly collaborative instincts

  • This role requires excellent communication and interpersonal skills, a high level of organizational ability and attention to detail

Primary Location
United States-California-La Jolla-
Other Locations
North America-United States-Pennsylvania-Spring House
Janssen Research & Development, LLC (6084)
Job Function
Requisition ID