Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies is recruiting for an Associate Scientific Director, Immunology Toxicology, located in La Jolla, CA.
At the Janssen Pharmaceutical Companies of Johnson & Johnson, we are working to create a world without disease. Transforming lives by finding new and better ways to prevent, intercept, treat and cure disease inspires us. We bring together the best minds and pursue the most promising science.
We are Janssen. We collaborate with the world for the health of everyone in it. Learn more at www.janssen.com and follow us @JanssenGlobal. Janssen Research & Development, LLC is part of the Janssen Pharmaceutical Companies.
Janssen Research & Development, LLC discovers and develops innovative medical solutions to address important unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, and cardiovascular and metabolic diseases. Please visit http://www.JanssenRnD.com for more information.
The Associate Scientific Director, Immunological Toxicology will evaluate potential immune system-related effects associated with large and small molecule therapeutics in our pipeline. The Associate Scientific Director will work with Project Toxicologists and nonclinical safety team to provide strategic and scientific input – to progress therapeutics from discovery to first-in-human and through development. As an Associate Scientific Director additional responsibility will include:
Provides immunological expertise to nonclinical safety teams, designs strategies to evaluate potential immunotoxicology risks, and participates in assessments. Strategies will include literature evaluation, as well as, direct experimental approaches performed in-house and at Contract Research Organizations (CROs).
Responsible for running the day to day lab operations by mentoring multiple lab based senior scientists and scientists including the career development of all employees within the department.
Interacts with CROs at multiple levels, including: transferring methods developed at Janssen, monitoring CRO validations, and the monitoring of immune endpoints during both GLP and non-GLP studies.
Independently designs, conducts and leads studies to evaluate the effects of immunomodulatory compounds using various in vivo and in vitro model systems including, but not limited to, cytokine assessment, immune response, flow cytometry and functional cell-based assays including human relevant complex physiological model systems.
Authors and reviews formal study reports in compliance with discovery data integrity principles.
Participates in communication of information and data presentation in oral and written format both in-house and at appropriate external forums.
Maintains an industry leading expertise in Immunotoxicology.
Maintains strong scientific network in academia and the pharmaceutical/biotechnology industry to enable external interactions, consulting and recruiting.
Provide an environment, which encourages the company's commitment to equal employment opportunity and the value of a diverse work force.
- PhD in
immunology, immunotoxicology, toxicology or related discipline with 6 years
of relevant experience OR M.S. degree in immunology, immunotoxicology,
toxicology or related discipline with 10+ years of relevant experience.
- Established expertise in
Immunotoxicology is required
- Expertise in immunological
techniques (e.g. flow cytometry, immunoassays) is required
- Deep scientific expertise in
immunology is preferred
Experience in pharmaceutical/biotechnology research management or related experience in drug development is required
Knowledge of GLPs is required
Knowledge of Health Authority regulations and guidelines for drug development (e.g. ICH, FDA, EMEA, PMDA) is preferred
Previous experience managing external partnerships (CRO’s) is required
Strong leadership skills with highly collaborative instincts
This role requires excellent communication and interpersonal skills, a high level of organizational ability and attention to detail
Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
United States-California-La Jolla-
Janssen Research & Development, LLC (6084)