Johnson & Johnson Careers

Senior Scientist, Bi-Specific Antibody Engineer

Spring House, Pennsylvania

Job Description

Requisition ID: 8341190227

Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies is recruiting for a Senior Scientist, Bi-Specific Antibody Engineer located in Spring House, PA.
At the Janssen Pharmaceutical Companies of Johnson & Johnson, we are working to create a world without disease. Transforming lives by finding new and better ways to prevent, intercept, treat and cure disease inspires us. We bring together the best minds and pursue the most promising science. We are Janssen. We collaborate with the world for the health of everyone in it. Learn more at and follow us @JanssenGlobal.  Janssen Research & Development, LLC is part of the Janssen Pharmaceutical Companies.
The Senior Scientist position is a leadership position within the Biologics Discovery team.  The successful candidate will drive biologics discovery in partnership with different therapeutic areas (TA) including oncology, immunology, metabolic diseases, neurology and infectious diseases. As a scientific leader in the department, the Senior Scientist will interact with other functional areas to provide molecular design for immunotherapeutics. The responsibilities also include therapeutic portfolio project leadership and cutting-edge molecular biology technology development.   The scope of this position encompasses:
  • Designing & building vectors to support multi-specific immunotherapeutics
  • Selecting, designing and optimizing domain-modules/scFv/Fab from antibodies for multi-specific immunotherapeutics
  • Leading portfolio project(s) from idea through IND-readiness in partnership with therapeutic area leadership
  • Executing molecular biology, such as in silico sequence fitness assessments, PCR-based cloning, construct design, library and/or site-directed mutagenesis for the much of the biologics portfolio
  • Developing high-sensitivity, high-throughput assays (protein and/or cell-based) for antibody and other therapeutics to select leads with excellent biophysical and manufacturing properties with reduced immunogenic potential
  • Leading and supervising research activities of bench scientist(s)
  • Presenting and defending scientific findings in cross-functional project teams/initiatives, drafts protocols and reports

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

Primary Location
United States-Pennsylvania-Spring House-Welsh & McKean Roads
Janssen Research & Development, LLC. (6084)
Job Function
Requisition ID