Johnson & Johnson Careers

POSTDOCTORAL RESEARCH FELLOW - NOVEL PLATFORM TO IDENTIFY THERAPEUTIC ANTIBODIES

Spring House, Pennsylvania
Administration


Job Description

Requisition ID: 7545180329

Janssen BioTherapeutics is seeking a highly motivated individual to develop a novel cell isolation platform to aid in the identification of therapeutic antibodies. 
Many multi-span and multi-subunit cell surface receptors that reside in the cell membrane are important in cell signaling, and could be highly desirable therapeutic targets. However, owing to the inherent difficulties in translating these membrane-bound proteins into effective antigen preparations, identifying therapeutic antibodies against these targets has been an immense challenge. A robust method for antibody-independent cell sorting platform could greatly facilitate antibody therapeutics discovery for these desirable targets.  The Postdoctoral Fellow will spearhead the development of a novel, antibody-independent cell isolation platform to enable antibody identification for complex membrane receptors.
At Janssen, postdoctoral fellows are trained by expert scientists working at the cutting edge of drug discovery.  Janssen BioTherapeutics supports a wide range of therapeutic areas including Oncology, Neuroscience, Cardiovascular and Metabolism, Immunology, and Infectious Diseases.  The successful candidate will learn from and contribute to an industry-leading drug discovery program that has brought numerous quality therapeutics to patients and significant contributions to human health. They will partner throughout the Janssen R&D organization and participate in cross-functional team discussions, gaining insight into many aspects of biotherapeutic discovery and development.  The Postdoctoral Fellow is expected to author papers on their research and present novel findings at scientific conferences. 
 
Key Objective:
To develop a novel antibody-independent cell isolation platform to enable antibody identification for complex membrane receptors.

Qualifications
Qualifications
  • Cell membrane biochemistry
  • Flow cytometry
  • Fluorescent cell sorting
Candidates must display an ability to independently design and execute research. In addition to a broad knowledge of biochemistry and cell biology, we are seeking an individual with deep intellectual curiosity, and excellent communication and interpersonal skills.

 

Primary Location
United States-Pennsylvania-Spring House-
Organization
Janssen Research & Development, LLC. (6084)
Job Function
Administration
Requisition ID
7545180329