Johnson & Johnson Careers

POSTDOCTORAL RESEARCH FELLOW - DESIGN AND DIRECTED EVOLUTION OF NOVEL IgG-LIKE MULTISPECIFICS FOR BBB TRANSCYTOSIS

Spring House, Pennsylvania
Administration


Job Description

Requisition ID: 7540180329

Janssen BioTherapeutics is seeking a highly motivated candidate to design and discover novel IgG-like multispecifics for Blood-brain barrier transcytosis


Janssen BioTherapeutics offers an exciting postdoctoral opportunity to team-up with seasoned scientists with a mission to improve health of humanity. The Postdoctoral Fellow will engage in the discovery and molecular engineering of Biotherapeutics for unmet medical needs. As an integral member of the Antibody Engineering/Bispecifics group to design and discover novel IgG-like multispecifics for blood-brain barrier (BBB) transcytosis by rational directed evolution techniques. Besides exploring the potential of the scaffold for a variety of therapeutic applications proposed project(s) offers scope to design and develop next-generation bispecific antibodies that have simple architecture and optimal balance of pharmacology, safety and manufacturability.


At Janssen, postdoctoral fellows are trained by expert scientists working at the cutting edge of drug discovery.  Janssen BioTherapeutics supports a wide range of therapeutic areas including Oncology, Neuroscience, Cardiovascular and Metabolism, Immunology, and Infectious Diseases.  The successful candidate will learn from and contribute to an industry-leading drug discovery program that has brought numerous quality therapeutics to patients and significant contributions to human health. They will partner throughout the Janssen R&D organization and participate in cross-functional team discussions, gaining insight into many aspects of biotherapeutic discovery and development.  The Postdoctoral Fellow is expected to author papers on their research and present novel findings at scientific conferences.


Key Objective:

To design and develop next-generation multispecific antibodies for BBB transcytosis 


Qualifications

Suitable candidates will have a Ph.D. in molecular biology, biochemistry, biophysics, immunology or a related discipline. Research experience in one or more of the following areas is preferred: 


Primary Location
United States-Pennsylvania-Spring House
Organization
Janssen Research & Development, LLC. (6084)
Job Function
Administration
Requisition ID
7540180329