Johnson & Johnson Careers

Scientist, Computational Biologist - Immunology Biomarkers

Spring House, Pennsylvania

Job Description

Requisition ID: 6979181108

Janssen Research and Development, L.L.C., a member of Johnson and Johnson's Family of Companies, is recruiting for a Scientist, Computational Biologist - Immunology Biomarkers to be located in Spring House, PA.

At the Janssen Pharmaceutical Companies of Johnson & Johnson, what matters most is helping people live full and healthy lives. We focus on treating, curing and preventing some of the most devastating and complex diseases of our time. And we pursue the most promising science, wherever it might be found.

Janssen Research & Development, LLC discovers and develops innovative medical solutions to address important unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, and cardiovascular and metabolic diseases. Please visit for more information.

We are Janssen. Our mission drives us. Our patients inspire us. We collaborate with the world for the health of everyone in it.

Thriving on a diverse company culture, celebrating the uniqueness of our employees and committed to inclusion. Proud to be an equal opportunity employer.

This position is within the Immunology Biomarkers department Inflammatory Bowel Disease (IBD) team. The role will involve working with the team to identify and develop biomarkers associated with therapeutic response, patient stratification, and disease monitoring. The candidate will lead the development of biomarker plans for clinical studies and will work with Clinical Operations to ensure that the plans are executed. He or she will analyze biomarker data sets, including transcriptomic, genetic, proteomic, and microbiome data generated in clinical or non-clinical studies. The position will require the analysis of multidimensional high content data sets, integration of these data sets with clinical metadata, and pathway analysis of differentially modulated biomarkers in these data sets. This role will also require strong communication and influencing skills as the scientist will sit on clinical trial teams working closely with functions such as clinical, data management, regulatory and global clinical operations to incorporate the biomarker strategy and operationalize all aspects of protocol development, sample collection and data generation/analysis.

The candidate must have strong analytical skills and experience with high-content data. Experience with predictive models and biomarker discovery is expected. Familiarity with human translational research, clinical studies, and patient samples is highly preferred. The candidate must have a background in biology or immunology and be proficient in the biological interpretation of data. Strong communication skills and the ability to interface with internal and external stakeholders, service providers, and scientific collaborators is a requirement.


Qualified candidates must have relevant experience in Computational Biology, Immunology, Biomedical Engineering, Bioinformatics or a related field. A Ph.D. degree is required.  Two or more years of relevant experience is preferred.

Essential functions:
• Strong computational skills and expertise in analyzing large datasets (e.g. transcriptomic, genetic, proteomic, microbiome).
• Proficiency in standard analytical platforms (e.g. SAS, R, Matlab, Omicsoft ArrayStudio).
• Experience in the integration of –omics datasets (e.g. genetic and microbiome) and expertise in predictive algorithms, biomarker discovery and/or diagnostic development.
• Proficiency in biology/immunology, preferably in autoimmune disease or IBD, and in the biological interpretation of data.
• Good communication and writing skills.
• Good organization skills and ability to handle multiple projects simultaneously is essential.

Primary Location
United States-Pennsylvania-Spring House-
Janssen Research & Development, LLC. (6084)
Job Function
Requisition ID