Johnson & Johnson Careers

Senior Scientist, Immunological Toxicology

Spring House, Pennsylvania
Toxicology Research

Job Description

Requisition ID: 5520181025

Janssen Research and Development, L.L.C., a member of Johnson and Johnson's Family of Companies, is recruiting for an Senior Scientist, Immunological Toxicology located in Spring House, PA.
At the Janssen Pharmaceutical Companies of Johnson & Johnson, what matters most is helping people live full and healthy lives. We focus on treating, curing and preventing some of the most devastating and complex diseases of our time. And we pursue the most promising science, wherever it might be found. 
Janssen Research & Development, LLC discovers and develops innovative medical solutions to address important unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, and cardiovascular and metabolic diseases. Please visit for more information. 
We are Janssen. Our mission drives us. Our patients inspire us. We collaborate with the world for the health of everyone in it.
Thriving on a diverse company culture, celebrating the uniqueness of our employees and committed to inclusion. Proud to be an equal opportunity employer.
The Senior Scientist in Immunological Toxicology (IT) will work as a member of IT to evaluate potential immune system-related risks associated with large and small molecule therapeutics in our pipeline.  The Senior Scientist will work under limited supervision to provide strategic and scientific input to multidisciplinary Project Teams – to progress therapeutics from discovery to first-in-human and beyond. As a Senior Scientist additional responsibility will include:
  • Provides immunological expertise to Nonclinical Safety Scientists, designs strategies to evaluate potential immunotoxicology risks under limited supervision and in partnership with other Scientists and participates in assessments. Strategies will include literature evaluation, as well as, direct experimental approaches performed in-house and at Contract Research Organizations (CROs). 
  • Actively performs bench-based science for evaluating immune system-related effects. 
  • Interacts with CROs at multiple levels, including: transferring methods developed at Janssen, monitoring CRO validations, and the monitoring of immune endpoints during both GLP and non-GLP studies.
  • Designs, conducts and leads studies to evaluate the effects of immunomodulatory compounds using various in vivo and in vitro model systems including, but not limited to, cytokine assessment, immune response, flow cytometry and functional cell-based assays following Data Integrity standards, and writes reports for regulatory submission.
  • Investigates and develops novel experimental methods/technologies, contributes to improvement of existing methods and develops new in vitro/in vivo models to enhance our understanding of potential immunotoxicology risk and translatability to humans in the clinic.
  • Participates in communication of information and data presentation in oral and written format to stakeholders.
  • Supports Immunological Toxicology Senior Leaders to provide strategic and technical leadership to the organization.
  • Implements novel in vitro and in vivo models to study immune-related effects and the translatability to human.
  • Maintains up-to-date expertise in Immunotoxicology.
  • Represents the organization to senior management and peer groups within Janssen and Johnson & Johnson.
  • Maintains strong scientific network in academia and the pharmaceutical/ biotechnology industry to enable external interactions, consulting and recruiting.
  • Responsible for the development of all employees within the department by supporting the development of Human Resources Planning (HRP) programs including management development and training to meet current and future business needs. 
  • Provides an environment, which encourages the company's commitment to equal employment opportunity and the value of a diverse work force.


Primary Location
United States-Pennsylvania-Spring House-1400�McKean�Road
Janssen Research & Development, LLC. (6084)
Job Function
Toxicology Research
Requisition ID