Johnson & Johnson Careers

Senior Scientist, Downstream Processing / Purification

Malvern, Pennsylvania

Job Description

Requisition ID: 3910180612

Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies is recruiting for an Senior Scientist, located in Malvern, PA.
At the Janssen Pharmaceutical Companies of Johnson & Johnson, what matters most is helping people live full and healthy lives. We focus on treating, curing and preventing some of the most devastating and complex diseases of our time. And we pursue the most promising science, wherever it might be found.  
Janssen Research & Development, LLC discovers and develops innovative medical solutions to address important unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, and cardiovascular and metabolic diseases. Please visit for more information.  
We are Janssen. Our mission drives us. Our patients inspire us. We collaborate with the world for the health of everyone in it.
Thriving on a diverse company culture, celebrating the uniqueness of our employees and committed to inclusion. Proud to be an equal opportunity employer.

The candidate for this position will lead and perform process development for the antibody purification processes within the API-Large Molecule group in Malvern, PA. The candidate’s primary responsibilities will include leading and participating in the design of experiments, executing the planned experiments, and optimizing the process steps to the target process scale. This will include laboratory and occasional pilot-scale scale chromatography and filtration. Additional responsibilities include but are not limited to the following:

  • Lead the design and execution of development studies to identify and determine appropriate conditions and ranges of (critical) process parameters for chromatographic purification & separation and several types of filtration
  • Record and analyze experimental data, verify data integrity and accuracy, and report/summarize findings to the project team, and also draft technical documents and perform technology transfer to collaboration partners. 
  • Work in a team environment as well as contributing individually to meet project timeline and objectives


  • A PhD in Chemical Engineering or Biological Sciences or Biochemistry with at least 3 years of relevant post-doctoral experience OR MS in Chemical Engineering or Biological Sciences or Biochemistry and with at least 12 years of relevant experience OR a BS in Chemical Engineering or Biological Sciences or Biochemistry and with at least 15 years of relevant experience is required
  • Knowledge and hands-on experience in downstream processing and purification of antibodies/recombinant protein therapeutics, in particular chromatography and filtration, are required
  • Exposure to analytical method development for in-process methods is preferred
  • Experience maintaining written records of work in the form of (electronic) notebooks, technical reports and protocols is required
  • Data reporting, ability to present findings to management, and experience with team-based collaborations is a must
  • Occasional weekend work may be required

Primary Location
United States-Pennsylvania-Malvern
Janssen Research & Development, LLC. (6084)
Job Function
Requisition ID