Johnson & Johnson Careers

Associate Scientific Director, Immunological Toxicology

Spring House, Pennsylvania
Toxicology Research

Job Description

Requisition ID: 3859180612

Janssen Research and Development, L.L.C., a member of Johnson and Johnson's Family of Companies, is recruiting for an Associate Scientific Director, Immunological Toxicology located in Spring House, PA with up to 20% travel.


At the Janssen Pharmaceutical Companies of Johnson & Johnson, what matters most is helping people live full and healthy lives. We focus on treating, curing and preventing some of the most devastating and complex diseases of our time. And we pursue the most promising science, wherever it might be found. 


Janssen Research & Development, LLC discovers and develops innovative medical solutions to address important unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, and cardiovascular and metabolic diseases. Please visit for more information. 


We are Janssen. Our mission drives us. Our patients inspire us. We collaborate with the world for the health of everyone in it.


Thriving on a diverse company culture, celebrating the uniqueness of our employees and committed to inclusion. Proud to be an equal opportunity employer.


The Associate Scientific Director, Immunological Toxicology will evaluate potential immune system-related effects associated with large and small molecule therapeutics in our pipeline.  The Associate Scientific Director will work with Project Toxicologists and nonclinical safety team to provide strategic and scientific input – to progress therapeutics from discovery to first-in-human and through development. As an Associate Scientific Director additional responsibility will include:

  • Provides immunological expertise to nonclinical safety teams, designs strategies to evaluate potential immunotoxicology risks, and participates in assessments. Strategies will include literature evaluation, as well as, direct experimental approaches performed in-house and at Contract Research Organizations (CROs). 
  • Interacts with CROs at multiple levels, including: transferring methods developed at Janssen, monitoring CRO validations, and the monitoring of immune endpoints during both GLP and non-GLP studies.
  • Independently designs, conducts and leads studies to evaluate the effects of immunomodulatory compounds using various in vivo and in vitro model systems including, but not limited to, cytokine assessment, immune response, flow cytometry and functional cell-based assays following Data Integrity standards, and writes reports for regulatory submission.   
  • Investigates and develops novel experimental methods/technologies, contributes to improvement of existing methods and develops new in vitro/in vivo models to enhance our understanding of potential immunotoxicology risk and translatability to humans in the clinic.
  • Participates in communication of information and data presentation in oral and written format both in-house and at appropriate external forums.
  • Maintains an industry leading expertise in Immunotoxicology.
  • Represents the organization to senior management and peer groups within Janssen and Johnson & Johnson.
  • Maintains strong scientific network in academia and the pharmaceutical/biotechnology industry to enable external interactions, consulting and recruiting.
  • Be a mentor/coach to key scientific staff and guide/enable their career/professional development.
  • Responsible for the development of all employees within the department by supporting the development of Human Resources Planning (HRP) programs including management development and training to meet current and future business needs. 
  • Provide an environment, which encourages the company's commitment to equal employment opportunity and the value of a diverse work force.


Primary Location
United States-Pennsylvania-Spring House
Janssen Research & Development, LLC. (6084)
Job Function
Toxicology Research
Requisition ID