Scientific Director, Discovery Support & Biophysical Chemistry Research

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Job Description

Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies is recruiting for a Scientific Director, Discovery Support & Biophysical Chemistry Research located in Spring House, PA.

At the Janssen Pharmaceutical Companies of Johnson & Johnson, we are working to create a world without disease. Transforming lives by finding new and better ways to prevent, intercept, treat and cure disease inspires us. We bring together the best minds and pursue the most promising science. We are Janssen. We collaborate with the world for the health of everyone in it. Learn more at and follow us @JanssenGlobal.  Janssen Research & Development, LLC is part of the Janssen Pharmaceutical Companies.


The Scientific Director, Discovery Support & Biophysical Chemistry Research, will manage two teams to support Janssen’s biologics early discovery pipeline.  They will design and implement broadly-based biophysical analyses aimed at characterizing the identity, binding affinity, and epitope of large panels of biologics in a high-throughput manner working in conjunction with the JBIO Antibody Generation Team.  Screening methods will include SPR, HDX epitope mapping, mass spectrometry and others.    In addition, the Director will manage a group of scientists focused on supporting the JBIO Exploratory Research group as well as internal and external collaborators by using biophysical techniques to characterize the quality of tool antibodies and reagents  and by using imaging mass spectrometry to support new target discovery.   He/she is expected to work closely with colleagues from the Exploratory Biology Group and Therapeutic areas to understand program needs and design studies appropriately. 


The candidate will help establish a strategy for the biophysical analysis of novel therapeutic modalities in a cell-based context. The ability to apply a strong, fundamental understanding of biophysical chemistry to applied research problems is necessary for success in this position.


This individual’s effort will drive biophysics innovation, support advancement of research projects into the portfolio, QC of molecular tools, and drive the analytical strategy for hits screening in the early discovery phase.


Essential Functions:

  1. Directly lead managers and indirectly manage employees of different levels.

  2. Review and approve internal documents and advise on the submission of scientific publications

  3. Contribute to hiring, promotions, pay adjustments, performance appraisals, development and other people related decisions

  4. Develop and maintain a close partnership with stakeholder departments.

  5. Exercise a highly complex level of independent judgment and execution which directly impacts the operational results of JBIO and is expected to influence across disciplines with senior leaders and external colleagues.

  6. Be responsible for, resource allocation, efficiency and productivity solutions.

  7. Set and monitor priorities, timeline and resources for their function, and contribute to hiring, promotions, pay adjustments, and performance assessments

  8. Be responsible for their group’s business-critical initiatives such as staff development, training, mentoring employees, etc

  • Education: Ph.D. in Biochemistry, Protein Chemistry, or related life science
  • Post-doctoral experience followed by 12+ years pharmaceutical/biotechnology business experience, or 3-5 years of experience performing progressively advanced duties at the Associate Director level
  • Expertise in SPR, LC-MS, and other biophysical platforms
  • Some cell-based biophysical chemistry experience is preferred.
  • Proven track record in leading scientific team(s) and direct people management experience.
  • Strong collaborative skills and the ability to work in a team environment.


Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability

Primary Location
United States-Pennsylvania-Spring House-Welsh & McKean Roads
Janssen Research & Development, LLC (6084)
Job Function
Requisition ID