Johnson & Johnson Careers

Scientist, Molecular and Cellular Pharmacology

San Diego, California

Job Description

Requisition ID: 1966180913

Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies is recruiting for a Scientist, Molecular and Cellular Pharmacology, located in La Jolla, CA.

At the Janssen Pharmaceutical Companies of Johnson & Johnson, what matters most is helping people live full and healthy lives. We focus on treating, curing and preventing some of the most devastating and complex diseases of our time. And we pursue the most promising science, wherever it might be found.  

Janssen Research & Development, LLC discovers and develops innovative medical solutions to address important unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, and cardiovascular and metabolic diseases. Please visit for more information.

The Lead Discovery team is a critical part of the Discovery Sciences (DS) organization in Janssen R&D, and is committed to the delivery of high quality chemical leads needed for the generation of small molecule clinical compounds in all five Janssen Therapeutic Area (TA) discovery teams.  This mission requires deep scientific expertise in various disciplines including chemistry, cellular pharmacology, and screening technologies coupled with an ability to work collaboratively with internal and external partners.  Building on a strong legacy of success, we are currently seeking an outstanding individual to join our team as a Scientist.  This position will report to the Director of the Ion Channel/GPCR/Transporter Pharmacology group.

Key Responsibilities:

  • Be a key member of the Ion Channel/GPCR/Transporter Pharmacology group. 
  • Provide expertise and experimental support to therapeutic area programs from target nomination through declaration of a clinical candidate.  
  • Characterize novel targets, develop physiologically-relevant cellular assays to characterize target engagement and downstream effects of small molecule modulators.
  • Elucidate options for hit ID approaches.
  • Collaborate with screening scientists on development of HTS assays.
  • Perform mechanism-of-action studies on validated hits. 
  • In lead optimization, provide receptor-ligand mechanistic data and insight, and analyze biochemical and cellular SAR.  


Do you strive to join an outstanding team that is dynamic and ever-changing? Is career growth and opportunity appealing to you? Apply to this opportunity today.

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

Primary Location
United States-California-San Diego-
Janssen Research & Development, LLC. (6084)
Job Function
Requisition ID