Johnson & Johnson Careers

Senior Scientist, Computational Biology

Spring House, Pennsylvania; Cambridge, Massachusetts

Job Description

Requisition ID: 1861190107

Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies is recruiting for a Senior Scientist, Computational Biology, for our site in Spring House, PA or Cambridge, MA.

At the Janssen Pharmaceutical Companies of Johnson & Johnson, what matters most is helping people live full and healthy lives. We focus on treating, curing and preventing some of the most devastating and complex diseases of our time. And we pursue the most promising science, wherever it might be found.
Janssen Research & Development, LLC discovers and develops innovative medical solutions to address important unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, and cardiovascular and metabolic diseases. Please visit for more information. 

We are Janssen. Our mission drives us. Our patients inspire us. We collaborate with the world for the health of everyone in it.

Thriving on a diverse company culture, celebrating the uniqueness of our employees and committed to inclusion. Proud to be an equal opportunity employer.

This candidate will join Functional Genomics, a group within the Translational Platform department of Discovery Sciences, to develop and apply state of the art approaches to functional genomic screening analysis. This effort will support the identification and development of small and large molecule therapeutics for disease indications, including Oncology, Immunology, Infectious Diseases, Neuroscience, and Cardiovascular and Metabolic Diseases. You will work in an exciting, interdisciplinary environment, overlapping the different stages of the discovery pipeline, by interacting with several internal and external groups. You should be highly self-motivated and will be expected to critically analyze and interpret data from a variety of sources (internal and external). You will provide analytical support for functional genomics screening efforts within the group, for the integration of that screening data with other ‘omic’ datasets and for the interpretation of that data into clear and concise recommendations for our partners. 

• Develop, apply and benchmark analytic tools and pipelines for pooled functional genomics screening data from both in vitro and in vivo experiments, including quality control.
• Use biostatistics and bioinformatics algorithms to integrate multiple levels of biological information together with functional genomic data, for new hypothesis generation, target identification and target prioritization.
• Provide clear interpretation of functional genomic screening data and propose pathways for further computational and biological validation to our therapeutic area partners and collaborators.
• Collaborate across multiple disciplines and contribute to various projects within the organization.
• Demonstrate creativity and apply novel approaches to solving scientific problems. Propose novel and actionable ideas, aligned with scientific strategies and demands.
• Keep up to date on new computational methodologies and incorporate into internal pipelines as appropriate. Keep current on literature related to his/her field.
• Communicate in a clear and professional manner, both in writing and orally.

• Master’s degree in Bioinformatics, Computational Biology, Molecular Biology, System Biology, or a related discipline with a minimum of 8 years of experience or a Ph.D. with 2 years or more of post-degree working experience in a biotech/ pharmaceutical setting, or similar environment is required.
• Experience with ‘omic’ or similar high-dimensional data analysis is required.
• Proficiency with R, Matlab or equivalent is required.
• Experience in other coding languages or interactive visualizations is a plus.
• Ability to interpret, troubleshoot and report on complex data is required.
• Ability to effectively present scientific data and concepts to international standards is required.
• Strong organizational skills including the ability to handle several projects at a time is required.
• Excellent interpersonal skills with the ability to interact effectively with people is required.
• Experience with functional genomic screening (RNAi or CRISPR/Cas9 screening, etc.) is preferred.
• Experience with large scale data processing, integration and meta-analysis is preferred.
• Drug discovery experience in a biotech or pharmaceutical environment is preferred.
• Experience with collaborating with external partners (e.g. contract research organizations and academics) is preferred
• This position can be based in Spring House, PA or Cambridge, MA and may require up to 10% of domestic and international travel

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

Primary Location
United States-Pennsylvania-Spring House-
Other Locations
North America-United States-Massachusetts-Cambridge
Janssen Research & Development, LLC. (6084)
Job Function
Requisition ID