Johnson & Johnson Careers

Associate Scientist

Cork, Ireland
R&D


Job Description

Requisition ID: 1805705656W


Position Title: BioTD-AD Bioassay Associate Scientist
Department: BioTD-AD
Report to: Team Lead, Bioassay, Bioassay and Early Development  Stability Sciences
Location: Cork
Travel: 5-10%

Company Summary: 
Janssen Sciences Ireland UC is a member of the Johnson & Johnson Group of companies and is a pioneer in the use of mammalian cells to manufacture monoclonal antibodies. At its facility in Cork.
BioTherapeutics Development Analytical Development Cork (BioTD-AD Cork) is a department responsible for Tox release testing, clinical release and stability testing for drug substance and drug product and stability management of the large molecule (therapeutic proteins) portfolio. In addition to clinical release & stability activities BioTD-AD Cork ais responsible for analytical support for large molecules through troubleshooting, investigations, manufacturing support and analytical method transfer. 

Position Summary: 
Reporting to the Team Lead, Bioassay BioTD-AD Cork, the person will be focused executing bioassays and process impurity assays used in the release and stability testing of the large molecule clinical pipline. while being responsible for testing and resolution of product related  issues in support of  the Bioassay and Early Development Stability Sciences team.

Main duties and responsibilities:  
  • Routine release and stability testing of binding assays (e.g. ELISA and TR-FRET), cell based bioassays (e.g ADCC assays), process impurities and identity assays for pre-clinical and clinical product development.
  • Execution of  process impurity assays (e.g. residual host cell protein (HCP), residual DNA (PCR techniques) and residual Protein A).
  • Completion of documentation in adherence to GMP.
  • Testing to support assay validation/qualification and other studies.
  • Laboratory support activities (e.g. reagent qualification), routine passaging of cell lines and general housekeeping.
  • Support other projects as assigned, e.g.continuous improvement, automation and operational excellence
  • Support troubleshooting and investigations.
  • Perform Data Trending to support investigations, demonstrate method capability and product profile.
  • Write SOP’s, protocols, work instructions and training modules. 
  • Other duties as assigned by team lead.
What we’re about:
We are passionate about our work and play vital roles across a range of professional disciplines, and care deeply about our customers and communities. At Johnson & Johnson our culture enables dynamic and impactful careers. We share a kind of DNA where we’re each:
• Committed to caring
• Responsible to our communities.
• Ready to apply our knowledge and know-how.
• Rare in our background and experiences.
• The drivers of our own success.
• Passionate about doing what’s right.

Make a unique mark in your career
If you want to be seen for the talent you bring to your work, be the driver of your own career, and work with others who share your real passion for caring and success, then we invite you to join the Johnson & Johnson Talent Community by visiting www.careers.jnj.com.

If you decide to apply for the position, any personal data which you provide shall be processed by Johnson & Johnson Medical, a Johnson & Johnson company. Your personal data shall be processed for the purposes of recruitment, recruitment policy and selection.

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

Qualifications

Key Skills and Competencies required: 
  • Practical analytical laboratory experience in a GLP/GMP environment is advantagous. 
  • Experience of  Bioassay/Cell Culture experience is advantagous .
  • Familiar with applicable cGMP and other business compliance regulations.
  • Customer focus and results and performance driven.
  • Sense of Urgency.
  • Ability to work well within team structures and provide leadership. 

Education and Experience: 
  • A minimum of a Degree in Molecular Biology, Biochemistry, Pharmacy or related scientific field is required.
  • Knowledge of computer programs such as MS Word, Excel and Minitab.
  • Good understanding of quality and attention to detail.

Primary Location
Ireland-Cork-Cork-
Organization
Janssen R&D Ireland (7566)
Job Function
R&D
Requisition ID
1805705656W