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Postdoc – Digital biomarkers
Requisition ID: 1805635912W
Janssen Research & Development, L.L.C., a Johnson & Johnson company, is recruiting for a Postdoctoral Fellow, Digital biomarkers, to be located at our Beerse site in Belgium.
Janssen Pharma R&D seeks an innovative postdoc with expertise in bio-signal and smartphone data processing, statistical and computational techniques, including experience in managing and analyzing longitudinal data, to strengthen our digital biomarker research. He/she will be part of the Computational Sciences group in the Discovery Sciences organization within Janssen Pharma R&D.
The candidate will be responsible for studying the role of digital biomarkers, obtained from different biosensors (as accelerometer, photoplethysmogram and others), phone (voice calls and SMS) and smartphone’s built-in sensors (GPS, wi-fi, Bluetooth, microphone, proximity sensor, etc.) in relation to clinical outcome in major depressive disorder.
He/she will be responsible for extracting meaningful information from different digital data streams and building multivariate models of relapse prediction/detection and disease deterioration.
The candidate should possess strong training and experience in quantitative methods applied to neuroscience or other related fields.
The candidate should possess outstanding communication skills as well as broad interests in neuroscience that will enable him/her to facilitate interactions between clinical and computational scientists.
He/she will work with key internal and external partners to define analytics strategy for managing multi-sensor data obtained during observation clinical trials using remote measurement technologies, use digital signal process to handle date streams from biosensors and extract variables of interest.
He/she will use machine learning to build models for relapse prediction/detection and, in collaboration with key partners, mine the data to identify meaningful digital biomarkers.
He/she will effectively communicate data and results to our stakeholders within and outside of J&J, publish high-quality research, and work effectively with colleagues across J&J sectors.The postdoc will span two years, with the possibility of an additional year. Where appropriate, the postdoc will participate in training and development sessions & workshops within Janssen/J&J, as well as attend and present at external conferences. He/she will receive guidance and mentoring to participate and contribute to ongoing efforts focused on the digital biomarker research.
A Ph.D. in in computational neuroscience, computer sciences, electrical or biomedical engineering, statistics or related discipline is required.
Strong programming (Python, R, MATLAB) and data management skills and demonstrated ability to deliver on objectives in defined timelines are required.
Knowledge of programming in Big Data environment (pyspark, sparkR) is a plus
Deep knowledge in digital bio-signal processing, time series modelling (gaussian processes), time to event modelling, machine learning (probabilistic graphical models, deep learning) and data mining is required.
Knowledge in audio signal processing, and analysis of ESM (experience sampling method) data is preferred.
Understanding of mood disorders is a plus.
Being independent, self-motivated and innovative and the ability to excel in a goal-oriented, multifaceted and fast-moving team environment are required.
Outstanding communication and interpersonal skills, with a successful track record of collaborating with multidisciplinary scientific teams is required.
Janssen Pharmaceutica N.V. (7555)