Johnson & Johnson Careers

Sr. Scientist / Principle Scientist

Shanghai, Shanghai
Product Development


Job Description

Requisition ID: 1700190759W

·       Provide scientific guidance to staff in CRO(s) when developing crystallization processes, enabling the timely delivery of API with the required quality attributes, both physical as well as chemical

·       Provide scientific guidance to scientists in CRO(s) when conducting polymorph screening, salt screening and solid form understanding and selection

·       Interact with various stakeholders outside the department, such as API small, Drug Product Development, Analytical Development and Clinical Supply Chain

·       Coordinate external activities (outsourcing)

·       Follow up of ongoing production batches via PAT monitoring

·       Troubleshooting of production batches

·       Representative for  Pharmaceutical Sciences with respect to API control strategy, including spec setting, IPC's, criticality analysis and process parameters

·       Ensure all filing and regulatory information is available and correct

·       Lead and participate in local or global technology teams 


Qualifications

·      PhD degree in Pharmaceutics, Chemistry, Chemical Engineering, Pharmacy or a related field with 10+ years of working experience

·      Sound knowledge and experience in pharmaceutical sciences, solid form (salt/polymorph) selection, pre-formulation and solid state characterization techniques (XRD, DVS, DSC, TGA, IR)

·      Profound knowledge and hands on experience on different types of crystallization (cooling, evaporative, anti-solvent …), advanced infrastructure (automated reactors and PAT tools, optional, nice to have) and a set of supporting key API particle tuning technologies.

·      Expert in the use of PAT tools such as Lasentec (FBRM), IR, Raman as well as in the in-depth data interpretation

·      Good project management capabilities

·      Demonstrated strategic thinking capabilities

·      Strong interpersonal skills to effectively communicate with external sites and various internal and external functional areas

·      Highly effective team member/player who can work in a matrix organization to accomplish assigned tasks

·      Fluent English (both spoken and written) and good English scientific writing skills

·      Chinese speaking is a must

·      This position will be based in Shanghai, China and may require up to 15% international and domestic travel.


Primary Location
China-Shanghai-Shanghai
Organization
J&J (China) Investments Ltd (7046)
Job Function
Product Development
Requisition ID
1700190759W