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Assistant Scientist, API Process Development

Malvern, Pennsylvania

Job Description

Requisition ID: 0846180612

Janssen Research & Development, LLC, a Johnson & Johnson Company, is hiring an Assistant Scientist, to be located in Malvern, PA.
Janssen Research & Development, L.L.C. develops treatments that improve the health and lifestyles of people worldwide. Research and development areas encompass novel targets in neurologic disorders, gastroenterology, oncology, infectious disease, diabetes, hematology, metabolic disorders, immunologic disorders, and reproductive medicine.
Janssen Pharmaceuticals, Inc., a pharmaceutical company of Johnson & Johnson, provides medicines for an array of health concerns in several therapeutic areas, including: attention deficit hyperactivity disorder (ADHD), cardiovascular disease, general medicine (acid reflux disease, infectious diseases), mental health (bipolar I disorder, schizophrenia), neurologics (Alzheimer’s disease, epilepsy, migraine prevention and treatment), pain management, and women’s health. Our ultimate goal is to help people live healthy lives. We have produced and marketed many first-in-class prescription medications and are poised to serve the broad needs of the healthcare market – from patients to practitioners, from clinics to hospitals. For more about Janssen Pharmaceuticals, Inc., one of the Pharmaceutical Companies of Johnson & Johnson, visit
Thriving on a diverse company culture, celebrating the uniqueness of our employees and committed to Diversity & Inclusion, Janssen Research & Development, LLC is proud to be an equal opportunity employer.
The candidate for this position will perform process development for the antibody Purification processes within the API-Large Molecule group in Malvern, PA. The candidate’s primary responsibilities will include participating in the design of experiments, executing the planned experiments, and optimizing the process steps to the target process scale. This will include laboratory and occasional pilot-scale scale bioreactors, chromatography, and filtration. The candidate will design and execute development studies to identify and determine appropriate ranges of (critical) process parameters for cell culture, to optimize growth and product production. The candidate will also design and execute development studies to identify and determine appropriate conditions and ranges of (critical) process parameters for chromatographic purification & separation and several types of filtration. The candidate will record and analyze experimental data, verify data integrity and accuracy, and report/summarize findings to the project team, and also draft technical documents and perform technology transfer to collaboration partners. The candidate is expected to work in a team environment as well as contributing individually to meet project timeline and objectives.

  • A BS in Chemical Engineering or Biological Sciences or Biochemistry or a related field, or an Associate degree in Chemical Engineering or Biological Sciences or Biochemistry or a related field with at least 3 years of relevant experience is required.
  • Knowledge of and hands-on experience with mammalian cell culture, bioreactors, bioreactor process development, and bioreactor data analysis is preferred.
  • Knowledge and hands-on experience with downstream processing and purification of antibodies, in particular chromatography and filtration is preferred.
  • Familiarity with and hands-on experience with analytical methods typically used in the manufacture and characterization of recombinant proteins is preferred.
  • It is required that the candidate be highly organized and capable of managing/pursuing multiple projects with some supervision.
  • Good written and verbal communication skills are required.
  • Experience maintaining written records of work in the form of laboratory notebooks (paper or electronic) is required.
  • The ability to report data, present findings to management is required. 
  • Experience with team-based collaborations is required.
  • Occasional weekend work is required as well as occasional work at a secondary facility in Springhouse, PA.

Primary Location
United States-Pennsylvania-Malvern
Janssen Research & Development, LLC. (6084)
Job Function
Requisition ID