Johnson & Johnson Careers

Senior Scientist

San Diego, California
Chemistry


Job Description

Requisition ID: 0335180119

Senior Scientist: Janssen Research & Development, LLC is seeking a Senior Scientist for our San Diego, California location. The position will be responsible for the design and synthesis of potential drug candidate molecules directed towards the discovery of medicines to treat neuropsychiatric diseases. Maintain a close interaction with the computer assisted design group, biologists, and pharmaceutical development scientists. Contribute to defining elements of regional, functional or new project strategies for Research & Development; create and manage complex research plans in the delivery of business results; analyze complex issues and improve, change, or adapt existing methods and techniques; and develop research solutions that require extensive analysis and detailed investigations. Supervision of research associates and CRO resources will also be required.

 

Qualified applicants will possess a PhD degree in Organic Chemistry or a related field, and 4 years of post-doctoral experience in medicinal chemistry. A qualified applicant will possess 4 years of experience with Varian and/or Bruker NMR spectroscopy, including proton, carbon, fluorine, DEPT, COSY, 2D NOESY, 1D NOE, APT, HSQC, and HMBC. Must possess 4 years of experience with variable temperature NMR experiments; 4 years of experience with LCMS, IR, and HPLC; and 4 years of experience with polarimetery. Must possess 4 years of experience with transition metal catalysis, enantioselective synthesis, and with methodology development and multistep synthesis. Must possess 4 years of experience performing milligram scale to multigram scale synthesis; 4 years of experience in the synthesis of small molecules and the optimization of their properties to access the central nervous system; 4 years of experience working on diverse target classes that include kinases, GPCRs and ion channels; and 4 years of experience in programs from the HTL to NME declaration. Must possess 4 years of experience with ChemDraw, MestRenova, ACD Labs, SciFinder, Reaxys, Pymol, 3DX, Prism and ELN electronic notebook. Less than 5% of domestic travel is required.

 

To apply for this position, please submit your resume via email, indicating Requisition Code 0335180119 to: Stephanie Manente (smanente@its.jnj.com).


Qualifications

Senior Scientist: Janssen Research & Development, LLC is seeking a Senior Scientist for our San Diego, California location. The position will be responsible for the design and synthesis of potential drug candidate molecules directed towards the discovery of medicines to treat neuropsychiatric diseases. Maintain a close interaction with the computer assisted design group, biologists, and pharmaceutical development scientists. Contribute to defining elements of regional, functional or new project strategies for Research & Development; create and manage complex research plans in the delivery of business results; analyze complex issues and improve, change, or adapt existing methods and techniques; and develop research solutions that require extensive analysis and detailed investigations. Supervision of research associates and CRO resources will also be required.

 

Qualified applicants will possess a PhD degree in Organic Chemistry or a related field, and 4 years of post-doctoral experience in medicinal chemistry. A qualified applicant will possess 4 years of experience with Varian and/or Bruker NMR spectroscopy, including proton, carbon, fluorine, DEPT, COSY, 2D NOESY, 1D NOE, APT, HSQC, and HMBC. Must possess 4 years of experience with variable temperature NMR experiments; 4 years of experience with LCMS, IR, and HPLC; and 4 years of experience with polarimetery. Must possess 4 years of experience with transition metal catalysis, enantioselective synthesis, and with methodology development and multistep synthesis. Must possess 4 years of experience performing milligram scale to multigram scale synthesis; 4 years of experience in the synthesis of small molecules and the optimization of their properties to access the central nervous system; 4 years of experience working on diverse target classes that include kinases, GPCRs and ion channels; and 4 years of experience in programs from the HTL to NME declaration. Must possess 4 years of experience with ChemDraw, MestRenova, ACD Labs, SciFinder, Reaxys, Pymol, 3DX, Prism and ELN electronic notebook. Less than 5% of domestic travel is required.

 

To apply for this position, please submit your resume via email, indicating Requisition Code 0335180119 to: Stephanie Manente (smanente@its.jnj.com).


Primary Location
United States-California-San Diego
Organization
Janssen Research & Development, LLC. (6084)
Job Function
Chemistry
Requisition ID
0335180119