Senior Associate Scientist, Protein Expressions/ Purification

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Job Description

Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies is recruiting for a Senior Associate Scientist, Protein Expressions/ Purification located in Spring House, PA.

At the Janssen Pharmaceutical Companies of Johnson & Johnson, we are working to create a world without disease. Transforming lives by finding new and better ways to prevent, intercept, treat and cure disease inspires us. We bring together the best minds and pursue the most promising science. We are Janssen. We collaborate with the world for the health of everyone in it. Learn more at and follow us @JanssenGlobal.  Janssen Research & Development, LLC is part of the Janssen Pharmaceutical Companies.


In this role you will be expected to coordinate key protein expression deliverables with external partners and serve as the main contact person for our outsourcing partners. You will communicate with internal stakeholders to gain clear alignment of project goals and objectives and then work closely with external vendors to ensure the delivery of proteins with the desired quality in a timely manner. In this capacity, you will help deliver a diversity of next-generation biotherapeutics candidates and ensure we can fully evaluate these molecules and technologies in the context of a robust and active therapeutic pipeline. Finally, you will also be asked to occasionally support at-the-bench deliverables where necessary including protein expression and purification.

As a successful candidate, you should be driven by an innate motivation to solve big problems and address the most pressing unmet medical needs. You will bring a deep knowledge and expertise in protein expression and chromatography methods as well as an understanding of biochemical analytical techniques. You should be able to collaborate with other scientists and excel in a fast-paced, dynamic, and matrixed research environment.

Key Responsibilities:

  1. Configure and align project deliverables with the specifics of proteins requested and identify proper external partner for quality service

  2. Monitor project progress and make timely updates to internal stakeholders

  3. Provide technical guidance and help troubleshoot as needed

  4. Contribute to internal benchtop expression and purification deliverables as a core member of the Expression Sciences team

  5. Maintain accurate laboratory notebooks in a timely fashion and prepare technical reports, summaries, protocols, etc.



  • B.S. or M.S. in Biochemistry, Chemistry, Biology or related areas in Life Sciences
  • B.S. with at least 5 years and M.S. with at least 2 years of relevant work experience is required

Experience and Skills:

  • Hands-on experience with either protein expression or protein purification & characterization is required
  • A strong working knowledge of gene-to-protein process is preferred
  • Experience with handling of external collaboration is preferred
  • Ability to work in a team-based environment with excellent interpersonal and communication skills
  • Ability to work independently and meet aggressive metric-driven timelines.
  • The successful candidate must demonstrate working knowledge of scientific principles and is able to learn new technologies.


Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability


Primary Location
United States-Pennsylvania-Spring House-Welsh & McKean Roads
Janssen Research & Development, LLC (6084)
Job Function
Requisition ID