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Scientist, Discovery Chemistry (1 of 2)

  • Titre Scientist, Discovery Chemistry (1 of 2)
  • Fonction R&D
  • Sous-fonction Chemistry
  • Lieu San Diego, California, United States
  • Date de mise en ligne
  • Référence 2306140024W
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Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies is recruiting for a Scientist in Discovery Chemistry in San Diego, CA.

At the Janssen Pharmaceutical Companies of Johnson & Johnson, we are working to create a world without disease. Transforming lives by finding new and better ways to prevent, intercept, treat and cure disease inspires us. We bring together the best minds and pursue the most promising science. We are Janssen. We collaborate with the world for the health of everyone in it. Learn more at and follow us @JanssenGlobal. Janssen Research & Development, LLC is part of the Janssen Pharmaceutical Companies.

The Global Discovery Chemistry group is committed to the delivery of high-quality drug candidates working with all five Janssen Therapeutic Areas (TAs). This mission requires deep scientific expertise in a number of disciplines including chemistry, cellular and molecular pharmacology, enzymology, and screening technologies coupled with an ability to work collaboratively with internal and external partners. Building on a strong legacy of success, we are currently seeking an outstanding individual to join our team as Scientist, Discovery Chemistry.

We are seeking an entry-level PhD chemist with excellent organic synthesis expertise to advance small molecule drug discovery programs toward the clinic. In this laboratory-based position, the successful candidate will partner with both internal and external medicinal chemistry teams to generate innovative solutions to synthetic and medicinal chemistry challenges within the context of small molecule drug discovery projects. They will maintain close interactions with computer-assisted design scientists, biologists, pharmacologists, and pharmaceutical development scientists. Strong people skills and the ability to thrive in a team and goal driven environment are key attributes.

This individual must also excel in communication and have strong interpersonal skills necessary to influence in a collaborative multidisciplinary environment.

Responsibilities of the Scientist include: 

Key Responsibilities:

  • Maintaining a high level of productivity in the laboratory setting.
  • Developing and executing clear synthetic strategies towards complex molecules using state-of-the-art synthetic methodologies.
  • Independently designing and synthesizing drug-like molecules utilizing medicinal chemistry knowledge and an understanding of ADME, pharmacokinetics, optimal physicochemical properties, and AI/ML predictive tools.
  • Collaboratively supporting the advancement of compounds through in vitro and in vivo studies to identify development candidates.
  • Collaboration with structure-based design groups to impact rational design of molecules.



  • PhD is required. Candidates who will be receiving their PhD by August 2024 will also be considered.

Experience and Skills:

  • Strong track record of achievement in the synthesis of complex molecules and/or synthetic methodology development, with deep knowledge of modern synthetic & analytical techniques is required.
  • Proven track record of scientific contributions including peer reviewed publications, patents and/or presentations is strongly preferred.
  • Experience with computational chemistry methods and biophysical techniques such as X-ray crystallography is preferred.
  • Independent thinking and the ability to effectively collaborate in a highly matrixed environment.
  • Excellent oral and written communication skills, including preparation of presentations.
  • Up to 10% travel is required.

The anticipated base pay range for this position is $102,000 to $163,300.

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

For more information on how we support the whole health of our employees throughout their wellness, career and life journey, please visit

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